JDRF Announces Partnership with Arecor Ltd to Support Development of a Stable, Rapid-Acting, Ultra-Concentrated Insulin

Improved insulins would enable the miniaturization of next-generation insulin-delivery devices for people with type 1 diabetes

The goal of the partnership is to accelerate the development of a stable, rapid-acting, ultra-concentrated insulin of up to 1,000 U/mL, which will not only offer a vastly superior mealtime insulin product for people requiring >200 U/day, but is also a critical step towards the advancement of the miniaturization of delivery devices, including next-generation artificial pancreas systems for people with type 1 diabetes.

Arecor and JDRF will work closely together on the project, and JDRF will provide Arecor with up to $900,000 in milestone funding over 12 months to complete product development to the end of pre-clinical pharmacokinetic/pharmacodynamic modelling (PK/PD).

Sarah Howell, CEO of Arecor, said, “We are delighted to be partnering with the JDRF as a leading global organization in type 1 diabetes research. This partnership will accelerate the development of Arecor’s reformulated, ultra-concentrated, rapid-acting insulin program, which is a critical unmet need in the drive towards new miniaturized insulin-delivery technology. Ultra-concentrated insulin is an important product component in our portfolio of next-generation diabetes products.”

“We are delighted to partner and collaborate with Arecor. There is a real need to improve the delivery and control of insulins, and the type 1 diabetes community is looking forward to smaller devices that can help them maintain glucose control safely and conveniently,” said Vincent Crabtree, director of Research Business Development at JDRF. “JDRF is supporting ultra-concentrated insulins that we believe will improve the overall quality of life for people living with type 1 diabetes.”

About JDRF

JDRF is the leading global organization funding type 1 diabetes (T1D) research. Our mission is to accelerate life-changing breakthroughs to cure, prevent and treat T1D and its complications. To accomplish this, JDRF has invested nearly $2 billion in research funding since our inception. We are an organization built on a grassroots model of people connecting in their local communities, collaborating regionally for efficiency and broader fundraising impact, and uniting on a national stage to pool resources, passion, and energy. We collaborate with academic institutions, policymakers, and corporate and industry partners to develop and deliver a pipeline of innovative therapies to people living with T1D. Our staff and volunteers throughout the United States and our six international affiliates are dedicated to advocacy, community engagement and our vision of a world without T1D. For more information, please visit jdrf.org or follow us on Twitter: @JDRF

About Arecor

Arecor’s diabetes product portfolio includes stable aqueous glucagon for emergency and artificial pancreas use, novel insulin formulations to deliver ultra-rapid acting insulin analogs and ultra-concentrated rapid acting insulin to enable the miniaturisation of devices.

In addition to its internal product portfolio, Arecor partners with leading pharmaceutical and biotech companies to deliver superior reformulations of their proprietary products, which would otherwise not be possible using conventional formulation science.