“Cardiac Development and Disease” Featuring Dr. Rameen Shakur

Dr. Rameen Shakur is a Jansen Fellow in Cardiology and Personalized Medicine at the Koch Institute for Integrative Science at MIT, and the Founder of Cambridge Heartwear Ltd. His academic research focuses on modeling and understanding cardiac development using iPSCs. Insights from his basic and clinical research spurred the development of Cambridge Heartwear Ltd., a medical device and algorithm company that uses AI and computer science for cardiovascular health.

Featured Products and Resources:
Webinar: Modeling Arrhythmias Using hPSC-Derived Cardiomyocytes and Tracking Their Excitability
STEMdiff™ Cardiomyocyte
The Stem Cell Science Round Up
New and Improved Genome Editing Tool – A new DNA editing technique, called prime editing, has been developed that doesn’t require double-strand breaks or donor DNA templates, overcoming some of the limitations of CRISPR.

Regulating Regeneration in Cold-Blooded Animals – Scientists have identified a gene that gives cold-blooded animals the ability to regenerate limbs, and suggest that the gene was lost by warm-blooded animals throughout evolution.

Mapping the Brain Development of Great Apes – Using human and ape brain organoids, investigators have found that human brains develop more slowly than ape brains, and identified human-specific gene expression.

Special Cells Help Regenerate Heart in Zebrafish – Researchers have identified a subset of cardiomyocytes in adult zebrafish that were shown to play a role in heart regeneration.

https://stemcellpodcast.com/ep-154-cardiac-development-and-disease-featuring-dr-rameen-shakur